Henry Pipes Barham, MD, FARS is a distinguished rhinologist and skull base surgeon whose research advances the understanding and treatment of complex sinonasal and upper airway disorders. His scholarly work spans clinical investigation, molecular studies, and translational science, contributing valuable insights into pediatric and adult otolaryngologic conditions. Dr. Barham has published influential studies on curcumin’s therapeutic potential in head and neck squamous cell carcinoma through modulation of the Akt/mTOR pathway, expanding the scientific dialogue on targeted cancer therapies. His research also explores collaborative surgical strategies in pediatric thyroidectomy, rare inflammatory and congenital sinonasal disorders, and unusual airway manifestations associated with genetic syndromes. Notably, he has contributed to advancing knowledge on idiopathic sclerosing inflammation, congenital nasolacrimal duct anomalies, and complex paranasal sinus tumors, enriching diagnostic and therapeutic approaches in these challenging cases. Dr. Barham’s work in sensory cell biology, including investigations into solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa, has deepened understanding of airway immunological and chemosensory mechanisms. Beyond peer-reviewed publications, he has produced educational surgical content for the American Rhinologic Society, supporting global dissemination of advanced rhinologic techniques. Through a strong commitment to clinical excellence, innovation, and academic contribution, Dr. Barham continues to influence best practices in rhinology and skull base surgery.
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Clark, C. A., Rong, Y., Rong, X., Shah, S., Barham, H., & Nathan, C. O. (2009). Curcumin inhibits HNSCC by modulating the Akt/mTOR pathway. Oral Oncology, 3(1).
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Wood, J. H., Partrick, D. A., Barham, H. P., Bensard, D. D., Travers, S. H., Bruny, J. L., & McIntyre, R. C., Jr. (2011). Pediatric thyroidectomy: A collaborative surgical approach. Journal of Pediatric Surgery, 46(5), 823–828.
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Barham, H. P., Dishop, M. K., & Prager, J. D. (2012). Idiopathic sclerosing inflammation presenting as sinusitis. Allergy & Rhinology (Providence), 3(2), e101–e104.
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Barham, H. P., Wudel, J. M., Enzenauer, R. W., & Chan, K. H. (2012). Congenital nasolacrimal duct cyst/dacryocystocele: An argument for a genetic basis. Allergy & Rhinology (Providence), 3(1), e46–e49.
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Barham, H. P., Said, S., & Ramakrishnan, V. R. (2013). Colliding tumor of the paranasal sinus. Allergy & Rhinology (Providence), 4(1), e13–e16.
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Barham, H. P., Cooper, S. E., Anderson, C. B., Tizzano, M., Kingdom, T. T., Finger, T. E., Kinnamon, S. C., & Ramakrishnan, V. R. (2013). Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosa. International Forum of Allergy & Rhinology, 3(6), 450–457.